Research Grant Recipients

Year Issuedsort ascending Project Title Grant Amount Types of Cancer Organization
2014 Understanding the Role of FOXD1 in Renal Cell Carcinoma Angiogenesis $178,409 Kidney Maine Medical Center Research Institute
2014 Genetic and Epigenetic Drivers of MDS Progression to sAML $50,000 Leukemia The Jackson Laboratory
2014 Characterization of Circulating Micro RNAs Involved in Lung Cancer Metastasis $50,000 Lung The Jackson Laboratory
2014 Optimization and Validation of a Preclinical Model for Myelodysplastic Syndrome $169,834 Cellular, Leukemia, Molecular The Jackson Laboratory
2014 Integrating Nanotechnology with Microfluidics to Diagnose and Monitor Disease Progression at the Molecular, Cellular and Tumor Level $168,309 All, Cellular, Molecular University of Maine
2014 Dissecting the Role of Tumor Cell Heterogeneity in Gioblastoma Therapy Response $50,000 Brain The Jackson Laboratory
2014 Logitudinal Analysis of Mammographic Breast Lesions and their Microenvironments $172,512 Breast University of Maine
2013 miR-590 - A Novel Candidate microRNA in Acute Myeloid Leukemia $168,906 Leukemia Maine Medical Center Research Institute
2013 Assessing Therapeutic Potential of a New Drug ICG-001 in Glioblastoma $50,000 Brain, Molecular The Jackson Laboratory
2013 Numb5 & Numb6 promote Invasive Behavior of Breast Cancer by Inducing Epithelial-Mesenchymal Transition $49,989 Breast, Cellular Maine Medical Center Research Institute
2013 The Role Of Spry1 And Spry4 In Triple-Negative Breast Cancer Differentiation And Cancer Stem Cell Self-Renewal $156,315 Breast Maine Medical Center Research Institute
2013 Inhibition Of Intercellular Adhesion Molecule-1 In Lung Cancer Cells By Selective Sirna Nanoparticles $48,300 Lung Husson University
2013 Anticancer Drug Delivery to Brain Using Cell Derived Exosome Nanovesicles $49,450 Brain Husson University
2013 Development of a Novel Small Molecule Inhibitor for Breast Cancer Treatment $169,861 Breast, Molecular Maine Medical Center Research Institute
2013 Cytometric Profiling Of The Non-Malignant Leukocytes In Patients With CLL: Addition Of A Control Group $49,900 Cellular, Leukemia Eastern Maine Medical Center Cancer Care
2013 The Role of the Kappa Opioid Receptor in Regulating Cancer Proliferation in Vitro and In Vivo $50,000 All University of New England
2013 The Maine Triple-Negative Breast Cancer Study $212,601 Breast The Jackson Laboratory
2013 Development of Optimized Ex Vivo Organotypic Slice Culture Systems $164,686 Brain, Breast, Colon, Other, Pancreatic The Jackson Laboratory
2013 Defining Susceptibility To Transformation By Epigenetic Landscape $49,999 Leukemia The Jackson Laboratory
2013 Notch Signaling In A Mouse Model Of Acute Promyelocytic Leukemia $50,000 Leukemia Maine Medical Center Research Institute
2012 The Role of IL-6 Signaling in Cancer-induced Bone Pain $139,633 Bone University of New England
2012 FoxC2 Function in glioma stem cells and Vasculature $84,000 All The Jackson Laboratory
2012 Feasibility of Using SEER-Medicare Data to Assess the Influence of ESA Policy Changes on Outcomes $55,936 All University of New England
2012 Inhibitory Effects of Insulin-like Growth Factor Binding Protein-4(IGFBP-4) on Melanoma Growth and Metastasis $73,848 Skin Maine Medical Center
2012 New Models for Lung Cancer Research $199,036 Lung The Jackson Laboratory
2012 Development of a Cancer Staging Tool Based on Viscoelastic and Spectrosphic Properties of Cystic Fluids $75,422 Pancreatic, Screening University of Maine
2012 3DMammoComp: Next Generation Computational Analysis of Breast Tomosynthesis $82,843 Breast University of Maine
2012 Improving Colorectal Cencer Screenings in Low-Income Primary Care Settings Using Shared Decision Making $97,860 Screening Maine Medical Center
2011 Inceptive Role of miR-199b in Acute Myeloid Leukemia $92,000 Leukemia Maine Medical Center
2011 The Molecular Structor of Arm 1 $73,087 Molecular Maine Institute for Human Genetics and Health
2011 Functional Analysis of Foxq1's Role in Tumor Vascularization $75,823 Molecular Mount Desert Island Biological Laboratory
2011 Imaging Glicoma Stem Cell Dynamics in Vivo $90,000 Screening The Jackson Laboratory
2011 Non-Psychotropic Cannabinoid2 Receptor Agonists Inhibit Breast Cancer Proliferation $105,197 Breast University of New England
2011 Validating Prediction Tools for Prostate Cancer Quality of Life Outcomes $71,029 Prostate Maine Medical Center
2011 Notch Regulation of the Tumor Supressor miR-145 in Breast Cancer Cells $94,184 Breast Maine Medical Center
2011 Small Molecule Inhibitors of Twist1 Function to Inhibit Tumor Progression $73,039 Molecular Maine Medical Center
2011 Targeted SiRNA Inhibition of Vascular Endothelial Growth Factors in Lung Cancer Cells $69,000 Lung Husson University
2011 FGF Export from Endothelial Cells: Protumorigenic Potential and Methods of Regulation $86,877 Cellular Maine Medical Center
2010 Notch Signaling in Medulloblastoma Initiation and Cancer Stem Cell Maintenance $90,000 Brain, Molecular The Jackson Laboratory
2010 Targeting Stromal Cell Interactions to Reduce Prostate Cancer $81,175 Prostate Maine Medical Center Research Institute
2010 Regulation of Hematopoietic Stem Cells by Heparin Binding Domain of IGFBP-2 $82,535 Cellular, Molecular Maine Medical Center Research Institute
2010 MicroRNA Expression during Lung Tumor Progression $90,000 Lung The Jackson Laboratory
2010 Role of Cryptic Activation Site within B1 Integrins in Breast Tumor Growth $91,919 Breast Maine Medical Center Research Institute
2010 Genetic Chemotherapy: Inducing Leukemia and Lymphoma Cell Self Destruction $67,500 Leukemia, Lymphoma The Jackson Laboratory
2010 Evaluating MicroRNA's as Prognostic Determinants in Stage II Colon Cancer $78,000 Colon Maine Center for Cancer Medicine
2010 Computationaal Pathology: 3-d Analysis of Chromosome Territories $80,000 Molecular, Screening University of Maine
2009 Functional Tests of PODXL's Contributions to Tumorigenesis $80,000 Molecular, Screening Maine Medical Center Research Institute
2009 Predicting Quality of Life Outcomes after Prostate Cancer Treatment $45,295 Prostate Maine Medical Center
2009 Role of MicroRNA-10b in Neurofibromatosis Type 1 Tumorigenesis and Progression $72,059 Cellular, Molecular Maine Institute for Human Genetics and Health
2009 Validating S100A6 as a Novel Marker and Potential Therapeutic Target of Brain Cancer Stem Cells $80,000 Brain The Jackson Laboratory
2009 Improved Cancer Detection through the use of Engineered Nanoparticle Bioconjugates $78,292 Screening University of Maine
2008 Wavelet-based image analysis of Mammograms $73,552 Breast University of Maine
2008 Genetic Model of TGFB Receptor-Dependent Supression of Prostate Cancer Metastasis $78,413 Prostate Maine Medical Center Research Institute
2008 Role of Delta Opioid Receptors in Bone Cancer $81,995 Bone University of New England
2008 Development Genomics of Lung Cancer $79,524 Lung The Jackson Laboratory
2008 Homologous Recombination Factor XRCC2 in B-Cell Genome Stability and Tumor Supression $79,696 Cellular, Molecular The Jackson Laboratory
2008 FGF-Mediated Tumor Growth Induced by Noth Signaling Inhibition $86,191 Cellular, Molecular Maine Medical Center Research Institute
2007 RECQL4 Protein-Protein Interactions in Human Osteosarcoma Cell Lines $71,000 Cellular, Molecular Eastern Maine Healthcare Systems
2007 Sprouty 4: a possible repressor of Id protein function in breast cancer $72,000 Breast Maine Medical Center Research Institute
2007 Twist dimers as markers of tumor metastasis $73,000 Molecular, Screening Maine Medical Center Research Institute
2007 Array-based Comparative Genomic Hybridization of Circulation Tumor Cells in Breast Cancer Patients Before & During Treatment $80,000 Screening Eastern Maine Healthcare Systems
2006 Molecular Predictors of Iressa Response in Lung Cancer Patients $68,241 Lung Maine Center for Cancer Medicine
2006 The Role of Src Kinases in Regulation of Stem Cell Survival in CML $75,000 Cellular, Leukemia, Molecular The Jackson Laboratory
2006 Reduction of breast cancer by the Notch signaling pathway $35,000 Breast Maine Medical Center
2006 Preventive and Therapeutic Effects of Vitamin D3 an its Membrane Receptor on Neoplastic Cells $76,206 Screening University of Maine
2006 Chromatin Reorganization in Pro-B Cell Lymphoma Nuclei $74,180 Lymphoma The Jackson Laboratory
2005 A Gene Expression Study for the Hormone Independent Growth Transition of Ovarian Cancer Cells in vivo $20,000 Ovarian The Jackson Laboratory
2004 Molecular Markers of Prognosis and Response to Therapy in Breast Cancer $70,500 Breast Maine Center for Cancer Medicine
2004 Malignant Ovarian Granulose Cell Teumorigenesis $37,165 Cervical The Jackson Laboratory
2004 Mechanisms of Arsenic Induced Human Lung and Bladder Cancer $45,745 Bladder, Lung University of Maine
2003 Parent-of-Origin Genetics in a Model of Ovarian Ganulosa Cell Tumorigenesis $35,500 Ovarian The Jackson Laboratory
2003 Protein Palmyitoylation: Examination and Characterization of the Protein Palitoyl-CoA Transferase Family of Dictyostelium $17,640 Cellular, Molecular University of Maine
2003 Molecular Indicators of Prognosis and Response to Therapy in Breast Cancer $60,700 Breast Maine Center for Cancer Medicine
2001 Cancer Genetics Research $87,000 All Maine Center for Cancer Medicine
2001 The Impact of Chemotherapy on Memory in Women with Breast Cancer $5,074 Breast University of New England
2001 Pilot Study of Post Breast Surgery Syndrome $9,292 Breast Mercy Hospital
2001 Cancer Treatment Outcome Data $50,000 Breast Maine Comprehensive Cancer Care